Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEQQLKDIISACDLAIQNEDFDTLMNYYSEDAVLVVKPG-MIARGKEEIKKAFITIANYFNHHIVPTQGKMILLEAGDTVLVLSQTLLDSDKKDSEYAMERRATYVFKKNAQGEWLCVIDNSYGTDLIGV 3F7S Chain:A ((7-127)) -ESEIRQLIERWMQAVRDRDIPGIIAPYADDIVAFDAIQALQFKGKSAYTAHWEMCMGMCTGPMVFELAQLTVHAAGDLALAHWLNRCGPG-DDESQCGFMRATVGYRRQ-GGQWQVIHEHWSA------

General information: TITO was launched using: RESULT: Template: 3F7S.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 473 -17539 -37.08 -146.16 target 2D structure prediction score : 0.59 Monomeric hydrophicity matching model chain A : 0.66 3D Compatibility (PKB) : -37.08 2D Compatibility (Sec. Struct. Predict.) : 0.59 1D Compatibility (Hydrophobicity) : 0.66 QMean score : 0.330

(partial model without unconserved sides chains): PDB file : Tito_3F7S.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3F7S-query.scw PDB file : Tito_Scwrl_3F7S.pdb: