Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSKVHQSACPLNCWDSCGFLVTVD-DGKVTKVDGDPNHP-ITEGKICGRGRMLETKTNSPDRLRYPMKKQN-----GEFVRISWEQALDEIADKLREIKETSETTAVLHSHDYA--NNGLLKALDQRFFNGYGGVTEIV--GSICWGSGIEAQSWDFGRSYGHGPLDIYNSKHVVVWGRNVSRTNMHL-YHHLQQVKKKGATITVIDPIFNPTAKLADRYISVKPGMDGWLAAAVLKVLIEMGRTDETFISEHSVGFDDVKELLKTVSLEEFIVKTETSMEELEYLAGLYAD-GPVSTFMGLGMQRYKNGGGTIRWIDALVAASGNVGIKGGGANFGNVQ-IGES--F------A------KTKL-TLP-----EL---------KTTSRSF--SM--MTQAEEVL--T-AADPA-IEMIIVTCGNPLTQVPNTNKVRQAFEKVPMTVAIDSIMTDTAELCDYVLPTATVFEEEDIYYSSMYHHYVQYGKKLVEPQGEAKSDSWIWSELAKRLGFGELFE-YSTQEFLEMGLSSLEAEDVTLERLKEKGHLPLPVKQ-VPWDDYQFLTPSGKFEFTSSLAEQKGFSGSLQLNVPEESV-FHNEE-------LAGKYPYTLLSIH-PQRSNHSQ--HVPFIEKL-QHVQVDISPDIAAGQDLQDGDEVVIFNDRGSMKGKVKVMKQAHAKTINIDEGMWAAF-------------GGS-VNALTNDT-NSDN-GMGSTLFD-CLVGLKKA 2E7Z Chain:A ((1-727)) ---KKHVVCQ-SCDINCVVEAEVKADGKIQTKSISEPHPTTPPNSICMKSVNADTIRTHKDRVLYPLKNVGSKRGEQRWERISWDQALDEIAEKLKKIIAKYGPESLGVSQTEINQQSEYG--TLRRFMNLLG-SPNWTSAMYMCIGNTAGVHRVTHG--SYSFAS-FADSNCLLFIGKNLSNHNWVSQFNDLKAALKRGCKLIVLDPRRTKVAEMADIWLPLRYGTDAALFLGMINVIINEQLYDKEFVENWCVGFEELKERVQEYPLDKVAEITGCDAGEIRKAAVMFATESPASIPWAVSTDMQKNSCSAIRAQCILRAIVGSFVN-GAEILGAPHSDLVPISKIQMHEALPEEKKKLQLGTETYPFLTYTGMSALEEPSERVYGVKYFHNMGAFMANPTALFTAMATEKPYPVKAFFALASNALMGYANQQNALKGLMNQDLVVCYDQFMTPTAQLADYVLPGDHWLERPVVQPNWEGIPFGNTSQQVVEPAGEAKDEYYFIRELAVRMGLEEHFPWKDRLELINYRISP---TGMEWEEYQKQYTYMSKLPDYFGPEGVGVATPSGKVELYSSVFEKL--------GYDPLPYYHEPLQTEISDPELAKEYPLILFAGLREDSNFQSCYHQPGILRDAEPDPVALLHPKTAQSLGLPSGEWIWVETTHGRLKLLLKHDGAQPEGTIRIPHGRWCPEQEGGPETGFSGAMLHNDAMVLSDDDWNLDPEQGLPNLRGGILAKAYKC

General information: TITO was launched using: RESULT: Template: 2E7Z.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 3985 64569 16.20 100.11 target 2D structure prediction score : 0.60 Monomeric hydrophicity matching model chain A : 0.71 3D Compatibility (PKB) : 16.20 2D Compatibility (Sec. Struct. Predict.) : 0.60 1D Compatibility (Hydrophobicity) : 0.71 QMean score : 0.462

(partial model without unconserved sides chains): PDB file : Tito_2E7Z.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2E7Z-query.scw PDB file : Tito_Scwrl_2E7Z.pdb: