Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNIIQGNLVGTGLKIGIVVGRFNDFITSKLLSGAEDALLRHGVDTNDIDVAWVPGAFEIPFAAKKMAETKKYDAIITLGTVIRGATTHYDYVCNEAAKGIAQAANTTGVPVIFGIVTTENIEQAIERAGT--KAGNKGVDCAVSAIEMANLNRSFE 2C92 Chain:A ((14-157)) --------DASGVRLAIVASSWHGKICDALLDGARKVAAGCGL--DDPTVVRVLGAIEIPVVAQELAR--NHDAVVALGVVIRGQTPHFDYVCDAVTQGLTRVSLDSSTPIANGVLTTNTEEQALDRAGLPTSAEDKGAQATVAALATALTLRELR

General information: TITO was launched using: RESULT: Template: 2C92.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 791 -111565 -141.04 -785.67 target 2D structure prediction score : 0.73 Monomeric hydrophicity matching model chain A : 0.79 3D Compatibility (PKB) : -141.04 2D Compatibility (Sec. Struct. Predict.) : 0.73 1D Compatibility (Hydrophobicity) : 0.79 QMean score : 0.609

(partial model without unconserved sides chains): PDB file : Tito_2C92.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2C92-query.scw PDB file : Tito_Scwrl_2C92.pdb: