Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTKKMGLLVMAYGTPYKESDIEPYYTDIRHGKRPSEEELQDLKDRYEFIGGLSPLAGTTDDQADALVSALNKAYADVEFKLYLGLKHISPFIEDAVEQMHNDGITEAITVVLAPHYSSFSVGSYDKRADEEAAKY-GIQLTHVKHYYEQPKFIEYWTNKVNETLAQIPEEEHKDTVLVVSAHSLPKGLIEKNNDPYPQELEHTALLIKEQSNIEHIAIGWQSEGNTGTPWLGPDVQDLTRDLYE-KHQYKNFIYTPVGFVCEHLEVLYDNDYECKVVCDDIGANYYRPKMPNTHPLFIGAIVDEIKSIF 2H1V Chain:A ((2-307)) SRKKMGLLVMAYGTPYKEEDIERYYTHIRRGRKPEPEMLQDLKDRYEAIGGISPLAQITEQQAHNLEQHLNEIQDEITFKAYIGLAHIEPFIEDAVAEMHKDGITEAVSIVLAPHFSTFSVQSYNKRAKEEAEKLGGLTITSVESWYDEPKFVTYWVDRVKETYASMPEDERENAMLIVSAHSLPEKIKE-FGDPYPDQLHESAKLIAEGAGVSEYAVGWQSEGNTPDPWLGPDVQDLTRDL-FEQKGYQAFVYVPVGFVADHLEVLYDNDYECKVVTDDIGASYYRPEMPNAKPEFIDALATVVLKK-

General information: TITO was launched using: RESULT: Template: 2H1V.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -144938 for 2588 contacts (-56.0/contact) + 2D Compatibility (PS) -33187 + (NN) -13265 + (LL) 288 1D Compatibility (HY) -32400 + (ID) 9250 Total energy: -232752.0 ( -89.94 by residue) QMean score : 0.552

(partial model without unconserved sides chains): PDB file : Tito_2H1V.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2H1V-query.scw PDB file : Tito_Scwrl_2H1V.pdb: