Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNTYAQESKLRLKTKIGADGRCVIEDNFFTPPFKLMAPFY-PKDDLAEIMLLAVSPGLMKGDAQDMQLNIGPNCKLRITSQSFEKIHNTEDGFASRDMHIVVGENAFLDFAPFPLIPFENAHFKGNTTISLRSSSQLLYSEIIVAGRVARNELFKFNRLHTKISILQDEKPIYYDNTILDPKTTNMNNMCMFDGYTHYLNLVLVNCPIELSGARELIEESEGVDGAVSKIASSHLCLKALAKGSEPLLHLREKIARLVTQTTTQKV--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 4I43 Chain:B ((882-2396)) GSGVMVEWLESRSFSPIPFPPLTYKNDTKILVLALEDLKDVYASKVRLNASEREELALIEEAYDNPHDTLNRIKKYLLTQRVFKPVDITPVYSVDPLEKITDAYLDQYLWYEADQRKLFPNWIKPSDSEIPPLLVYKWTQGINNLSEIWDVSRGQSAVLLETTLGEMAEKIDFTLLNRLLRLIVDPNIADYITAKNNVVINFKDMSHVNKYGLIRGLKFASFIFQYYGLVIDLLLLGQERATDLAGPANNPNEFMQFKSKEVEKAHPIRLYTRYLDRIYMLFHFEEDEGEELTDEYLAENPDPNFENSIGYNNRKCWPKDSRMRLIRQDVNLGRAVFWEIQSRVPTSLTSIKWENAFVSVYSKNNPNLLFSMCGFEVRILPRQRMEENDEGVWDLVDERTKQRTAKAYLKVSEEEIKKFDSRIRGILMASTTFTKVAAKWNTSLISLFTYFREAIVATEPLLDILVKGETRIQNRVKLGLNSKMPTRFPPAVFYTPKELGGLGMISASHILIPASDLSWSKQTDTGITHFRAGMTHEDEKLIPTIFRYITTWENEFLDSQRVWAEYATKRQEAIQQNRRLAFEELEGSWDRGIPRISTLFQRDRHTLAYDRGHRIRREFKQYSLERNSPFWWTNSHHDGKLWNLNAYRTDVIQALGGIETILEHTLFKGTGFNSWEGLFWLSQIPNRRFTLWWSPTINRANVYVGFLVQLDLTGIFLHGKIPTLKISLIQIFRAHLWQKIHESIVFDICQILDGELDVLQIESVTKETVHPRKSYKMNSSAADITMESVHEWEVSKPSLLHETNDSFKGLITNKMWFDVQLRYGDYDSHDISRYVRAKFLDYTTDNVSMYPSPTGVMIGIDLAYNMYDAYGNWFNGLKPLIQNSMRTIMKANPALYVLRERIRKGLQIYQEPFLNSSNYAELFNNDIKLFVDDTNVY------RVTVHKTFEG------NVATKAINGCIFTLNPKTG--HLFLKIIHTSVWAG-----QKRLSQLAKWKTAEEVSALVRSLP--KEEQPKQIIVTRKAMLDPLEVHMLDFPN--------IAIRPTELRLPFSAAMSIDKLSDVVMK------------ATEPQMVLFNIYDDWLDRISSYTAFSRLTLLLRALKTN----EESAKMILLSDP------TITIKSYHLWPSF--TDEQWITIESQMRDLILTEYGRKYNVNISALTQTESSKNEWRKSAIANTLLYLRLKNIYVSADDFVEEQNVYVLPKNLLKKFIEISDVKIQVAAFIYGMSAKDHPKVKEIKTVVLVPQLGHVGSVQISNIPDIGDLPDTEGLELLGWIHTQTEELKFMAASEVATHSKLFADKKRDCIDISIFSTPGSVSLSAYNLTDEGYQWGEENKDIMNVLSEGFEPTFSTHAQLLLSDRITGNFIIPSGNVWNYTFMGTAFNQEGDYNFKYGIPLEFYNEMHRPVHFLQFS

General information: TITO was launched using: RESULT: Template: 4I43.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -81237 for 1480 contacts (-54.9/contact) + 2D Compatibility (PS) -21913 + (NN) 1221 + (LL) 3492 1D Compatibility (HY) -10400 + (ID) 1750 Total energy: -110587.0 ( -74.72 by residue) QMean score : 0.273

(partial model without unconserved sides chains): PDB file : Tito_4I43.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4I43-query.scw PDB file : Tito_Scwrl_4I43.pdb: