Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MAKENLPIVFGPVLSRRFGKSLGVDLSPSKKQCNYNCIYCELGK-AKPIE-RMEEVIKVETLISTIQNALNN----LT-----------TPIDVLTITANGEPTLYPHLLELIQSIKPFLKGVKTLILSNGSLFYEPKVQQALK--EFDIVKFSLDAIDLKAFERVDKPYSK-DINKILEGILSFSQIYQGQLVAEVLLIKGVNDSANNLKLIADFLKKINTARVDLSTIDRPSSFK-----APKLSEDELLKCSLFFEGLCVSLPKRSTAQAKKLVSCGIDELLALISRRPLSAEEAPLILDPNAFKHLETLLNHKQITIKKVGSLEFYCAF 2YX0 Chain:A ((62-304)) -------KFYGIHSHRCL------QMTPVLAWCTHNCIFCWRPMENFLGTELPQPWDDPAFIVEESIKAQRKLLIGYKPKVDKKKFEEAWNPTHAAISLSGEPMLYPYMGDLVEEFHK--RGFTTFIVTNGTIPER-LEEMIKEDKLPTQLYVSITAPDIETYNSVNIPMIPDGWERILRFLELMRDL-PTRTVVRLTLVKG--ENMHSPEKYAKLILKARPMFVEAKAYM------NRLTINNMPSHQDIREFAEALVKHLPGYHIEDEYEPSRVVLIMRDDVDPQGTGVEGRFIKH-----------------------------------

General information: TITO was launched using: RESULT: Template: 2YX0.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -74446 for 1629 contacts (-45.7/contact) + 2D Compatibility (PS) -22532 + (NN) -8974 + (LL) 3820 1D Compatibility (HY) -6800 + (ID) 1850 Total energy: -110782.0 ( -68.01 by residue) QMean score : 0.433

(partial model without unconserved sides chains): PDB file : Tito_2YX0.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2YX0-query.scw PDB file : Tito_Scwrl_2YX0.pdb: