Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTVRYQIEQLGDSAMMIRFGEEINEQVNGIVHAAAAYIEEQPFPGFIECIPAFTSLTVFYDMYEVYKHLPQGISSPFESVKRDVEERLAEIAEDYEVNRRIVEIPVCYGGEFGPDLEEVAKINQLSPEEVIDIHTNGEYVVYMLGFAPGFPFLGGMSKRIAAPRKSSPRPSIPAGSVGIAGLQTGVYPISTPGGWQLIGKTPLALFRPQENPPTLLRAGDIVKFVRISEKDYHAYKEESN 3OPF Chain:B ((7-198)) ----------------LRFGEGVSEEANRRALALAEALLRAPPPGLLDAVPAYGVLYLEYD--------------PRRLSRGRLLRLLKGLPQERAEEGRVVEIPVRYDGE---DLPEVASRLGLSLEAVKALHQKPLYRVYALGFTPGFPFLAEVEPALRLPRKPHPRPRVPAHAVAVAGVQTGIYPLPSPGGWNLLGTSLVAVYDPHRETPFLLRPGDRVRFL---------------

General information: TITO was launched using: RESULT: Template: 3OPF.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 936 -120641 -128.89 -628.34 target 2D structure prediction score : 0.54 Monomeric hydrophicity matching model chain B : 0.75 3D Compatibility (PKB) : -128.89 2D Compatibility (Sec. Struct. Predict.) : 0.54 1D Compatibility (Hydrophobicity) : 0.75 QMean score : 0.541

(partial model without unconserved sides chains): PDB file : Tito_3OPF.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3OPF-query.scw PDB file : Tito_Scwrl_3OPF.pdb: