Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MAVKKVVTHPAEVLETPAETVTVFDKKLKKLLDDMYDTMLEMDGVGLAAPQIGILKRAAVVEIGDDRG-RIDLVNPEILEKSGEQTGI-EGCLSFPNVYGDVTRADYVKVRAFNRQGKPFILEARGFLARAVQHEMDHLDGVLFTSKISKYYTEDELADMEG 3K6L Chain:B ((2-148)) -SVLQVLHIPDERLRKVAKPVEEVNAEIQRIVDDMFETMYAEEGIGLAATQVDIHQRIIVIDVSENRDERLVLINPELLEKSGE-TGIEEGCLSIPEQRALVPRAEKVKIRALDRDGKPFELEADGLLAICIQHEMDHLVGKLFMDYLS-------------

General information: TITO was launched using: RESULT: Template: 3K6L.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 718 -70167 -97.72 -483.91 target 2D structure prediction score : 0.51 Monomeric hydrophicity matching model chain B : 0.82 3D Compatibility (PKB) : -97.72 2D Compatibility (Sec. Struct. Predict.) : 0.51 1D Compatibility (Hydrophobicity) : 0.82 QMean score : 0.477

(partial model without unconserved sides chains): PDB file : Tito_3K6L.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3K6L-query.scw PDB file : Tito_Scwrl_3K6L.pdb: