Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MGNTMCPKMESAFSLLGKRWNGLIIHVLM---DGPKRFKEITETIPMISQKMLAERLKELEQNEIVERQVLPETPVKVIYTLTEKGTALQAVFQEMQAWADQFCEPGDTVCEEEK 4HQE Chain:B ((7-110)) ----VCPYLEETFKILGRSWNGLIINYLSRCNDCSAHFSDMKRDLKTITPRALSLKLSELAQWELVEKQIISTSPVQIIYVLTEKGKALAEALHPIEAWAQSYVDLTD-------

General information: TITO was launched using: RESULT: Template: 4HQE.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 321 -8946 -27.87 -88.57 target 2D structure prediction score : 0.63 Monomeric hydrophicity matching model chain B : 0.83 3D Compatibility (PKB) : -27.87 2D Compatibility (Sec. Struct. Predict.) : 0.63 1D Compatibility (Hydrophobicity) : 0.83 QMean score : 0.613

(partial model without unconserved sides chains): PDB file : Tito_4HQE.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4HQE-query.scw PDB file : Tito_Scwrl_4HQE.pdb: