Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKKLKVMTVFGTRPEAIKMAPLVLELKKYPE-IDSYVTVTAQHRQMLDQVLDAFHIKPDFDLNIMKERQTLAEITSNALVRLDELFKDIKPDIVLVHGDTTTTFAGSLAAFYHQIAVGHVEAGLRTGNKYSPFPEELNRQMTGAIADLHFAPTGQAKDNLLKENKKADSIFVTGNTAIDALNTTVRDGYSHPVLDQVGEDKMILLTAHRRENLGEPMENMFKAIRRIVGEFEDVQVVYPVHLNPVVREAAHKHFGDSDRVHLIEPLEVIDFHNFAAKSHFILTDSGGVQEEAPSLGKPVLVLRDTTERPEGVEAGTLKLAGTDEENIYQLAKQLLTDPDEYKKMSQASNPYGDGEASRRIVEELLFHYGYRKEQPDSFTGK 3BEO Chain:B ((7-373)) -ERLKVMTIFGTRPEAIKMAPLVLELQKHPEKIESIVTVTAQHRQMLDQVLSIFGITPDFDLNIMKDRQTLIDITTRGLEGLDKVMKEAKPDIVLVHGDTTTTFIASLAAFYNQIPVGHVEAGLRTWDKYSPYPEEMNRQLTGVMADLHFSPTAKSATNLQKENKDESRIFITGNTAIDALKTTVKETYSHPVLEKLGNNRLVLMTAHRRENLGEPMRNMFRAIKRLVDKHEDVQVVYPVHMNPVVRETANDILGDYGRIHLIEPLDVIDFHNVAARSYLMLTDSGGVQEEAPSLGVPVLVLRDTTERPEGIEAGTLKLAGTDEETIFSLADELLSDKEAHDKMSKASNPYGDGRASERIVEAILKHF-------------

General information: TITO was launched using: RESULT: Template: 3BEO.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 2220 -4737 -2.13 -12.94 target 2D structure prediction score : 0.69 Monomeric hydrophicity matching model chain B : 0.93 3D Compatibility (PKB) : -2.13 2D Compatibility (Sec. Struct. Predict.) : 0.69 1D Compatibility (Hydrophobicity) : 0.93 QMean score : 0.566

(partial model without unconserved sides chains): PDB file : Tito_3BEO.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3BEO-query.scw PDB file : Tito_Scwrl_3BEO.pdb: