Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKKRMLDVLMLVIGAFFFALAVNLFAIPNDLGEGGVTGITLILYYLFQWSPGVTNFILNAFLLLIGYKFLDGKTTVYTIIAVAANSLFLHLTHGWSIPSDELIINTIFAGVFAGVGIGMIIRVGGTTAGSAILARIANKYLDWNISYALLFFDLIVVFSSYFIIGAEKMMFTIVMLYIGTKVMDFIIEGLNTKKAITVISEN--KSEIAEQVNTLMDRGVTIL--SGKGNY-------TG-------QSKEILYIVINKQELSMLKKIIRSCDK-----KAFVIVHDVRDVFGEGFVDISK 2J9C Chain:A ((5-106)) --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KVEAIIRPEKLEIVKKALSDAGYVGMTVSEVKGRGVQGGIVERYRGREYIVDLIPKVKIELVVKEEDVDNVIDIICENARTGNPGDGKIFVIPVERVVRVRT-----

General information: TITO was launched using: RESULT: Template: 2J9C.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 262 10715 40.90 135.63 target 2D structure prediction score : 0.72 Monomeric hydrophicity matching model chain A : 0.44 3D Compatibility (PKB) : 40.90 2D Compatibility (Sec. Struct. Predict.) : 0.72 1D Compatibility (Hydrophobicity) : 0.44 QMean score : 0.648

(partial model without unconserved sides chains): PDB file : Tito_2J9C.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2J9C-query.scw PDB file : Tito_Scwrl_2J9C.pdb: