Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEQQLKDIISACDLAIQNEDFDTLMNYYSEDAVLVVKPGM--IARGKEEIKKAFITIANYFNHHIVPTQGKMILLEAGDTVLVLSQTLLDS--DKKDSEYAMERRATYVFKKNAQGEWLCVIDNSYGTDLIGV 5IG3 Chain:A ((347-472)) -KQEIIKVTEQLIEAISNGDFESYTKMCDPGMTAFEPEALGNLVEGLDFHRFYFENLWSRNSKPVHTTILNPHIHLMGDESACIAYIRITQYLDAGGIPRTAQSEETRVWHRR-DGKWQIVHFHRSGA-----

General information: TITO was launched using: RESULT: Template: 5IG3.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 449 4700 10.47 38.52 target 2D structure prediction score : 0.64 Monomeric hydrophicity matching model chain A : 0.61 3D Compatibility (PKB) : 10.47 2D Compatibility (Sec. Struct. Predict.) : 0.64 1D Compatibility (Hydrophobicity) : 0.61 QMean score : 0.363

(partial model without unconserved sides chains): PDB file : Tito_5IG3.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5IG3-query.scw PDB file : Tito_Scwrl_5IG3.pdb: