Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MAGRPLHAFEVVATRHLAPHMVRVVLGGSGFDTF---VPSDFTDSYIKLVFVDDDVDVGRLPRPLTLDSFADLPTAKRPPVRTMTVRHVDAAAREIAVDIVLHGEHGVAGPWAAGAQRGQPIYLMGPGGAYAPDPAADWHLLAGDESAIPAIAAALEALPPDAIGRAFIEVAGPDDEIGLTAPDAVEVNWVYRGGRADLVPEDRAGDHAPLIEAVTTTAWL-PGQVHVFIHGEAQAVMHNLRPYVRNERGVDAK-WASSISGYWRRGRTEEMFRKWKKELAEAEAGTH 4YHB Chain:A ((14-267)) --PLKSRLLEVVNVRRITPRMVRVDLGGSDIAGLRSDNF----ADHVKLWFPNPETGEHVLPVVE-DDRC-LNFRAPGVIYRDYTVRRFDAKARLLTIDFVVHD-NGPGGRWAATAQPGDRLGVLGPRGTVYYP-EADHYVLLADETALPAAARRIEELPRDASVTAFFEVADAAEEQELDAPEGAEITWLHRNGAAPGTT----D----LLLRALEQTEFPKGRVFVWAGGEAD-ALKPIRRLLKE-RGLV-RGRDFEVDGYWRRGVSNLDHHA-------------

General information: TITO was launched using: RESULT: Template: 4YHB.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -151252 for 1964 contacts (-77.0/contact) + 2D Compatibility (PS) -27223 + (NN) -13121 + (LL) 2356 1D Compatibility (HY) -11600 + (ID) 4300 Total energy: -205140.0 ( -104.45 by residue) QMean score : 0.454

(partial model without unconserved sides chains): PDB file : Tito_4YHB.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4YHB-query.scw PDB file : Tito_Scwrl_4YHB.pdb: