Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MWFRNLLVYRLTQDLQLDADSLEKALGEKSARPCASQELTTYGFTAPFGKGPDAPLVHVSQDFFLISARKEERILPGSVVRDALKEKVDEIEAQQMRKVYKKERDQLKDEIVQTLLPRAFIRRSSTFAAIAPSLGLILVDSAS--------AKKAEDLLSTLREALGSLPVRPLSVKVAPTATLTDWVKTQEAAGDFHVLDECELRDTHEDGGVVRCKRQDLTSEEIQLHLTAGKLVTQLSLAWSDKLSFVLDDKLAVKRLRFEDLLQEQAEKDGGEDALGQLDASFTL----MMLTFAEFLPALFEALGGEEIPQGV------ 2DOR Chain:A ((1-311)) MLNTTFANAKFANPFMNASG-----VHCMTIEDLEELKASQAGAYITKSSTLEKREGNPLPRYVDLE--------LGSINSMGLPNLGFDYYLDYVLKNQKENAQEGPIFFSIAGMSAAENIAMLKKIQESDFSGITELNLSCPNVPGKPQLAYDFEATEKLLKEVFTFFTKPLGVKLPPYFDLVHFDIMAEILNQFPLTYVNSVNSIGNGLFIDPEAESVVIKPKDGFGGIGGAYIKPTALANVRAFYTRLKPEIQIIGTGGIETGQDAFEHLLCGATMLQIGTALHKEGPAIFDRIIKELEEIMNQKGYQSIADFHGKLKSL

General information: TITO was launched using: RESULT: Template: 2DOR.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) 39223 for 2524 contacts (15.5/contact) + 2D Compatibility (PS) -31038 + (NN) -9805 + (LL) 1456 1D Compatibility (HY) 400 + (ID) 1400 Total energy: -1164.0 ( -0.46 by residue) QMean score : 0.146

(partial model without unconserved sides chains): PDB file : Tito_2DOR.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2DOR-query.scw PDB file : Tito_Scwrl_2DOR.pdb: