Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNSKYKDVMMNDDLDSTTKQEALKYHIRG--GNPGKISILPTKSLSTQYDLSLAYSPGVAAPCLEIAKNPDVVYDYTAKSNCVAVISNGTAVLGLGNIGPLASKPVMEGKAMLFKRFADIDAVDIEVDTENIEDFINAVRYLGPSWGGINLEDIRSPDCFIIEKRLNELMDIPVFHDDQHGTAVVVAAGIENALDIAGKKLEDVKIIMNGAGAAGIACLEILKSMGAK--NIVLCDKQGVIYKGRNEDMNEWK---------EKYATDTKERSLLDAIKDTDVFIGLS--AKDALNEEMLKNMGQNPIIFALANPDPEVRPELAKSVRPDAIIATGRSDYNNQVNNVMGFPYIFRGALDVHAMTINNEMKIAAADAIAKLAREPAPDEISAVYGGRKMSYGREYIIPTPFDPRLVSIVSPAVAKAAVCSGVAKKEIQ-DW-SKYANQLKSRLANALNTLNLLSSQY 2DVM Chain:B ((3-432)) ------------------REKALEFHKNNFPGN-GKIEVIPKVSLESREELTLAYTPGVAEPCKEIARDPGKVYEYTSKGNLVAVVSDGSRILGLGNIGPLAGLPVMEGKALLFKRFGGVDAFPIMIKEQEPNKFIDIVKAIAPTFGGINLEDIASPKCFYILERLREELDIPVFHDDQQGTAAVVLAGLLNALKVVGKKISEITLALFGAGAAGFATLRILTEAGVKPENVRVVELVNGKPRILTSDLDLEKLFPYRGWLLKKTNGENIEGGPQEALKDADVLISFTRPGPGVIKPQWIEKMNEDAIVFPLANPVPEILPEEAKKAG-ARIVATGRSDYPNQINNLLGFPGIFRGALDVRARTITDSMIIAAAKAIASIVEEPS----------------EENIIPSPLNPIVYAREARAVAEEAMKEGVARTKVKGEWVEEHTIRLIEFYENVIAPINKKRREY

General information: TITO was launched using: RESULT: Template: 2DVM.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -196342 for 3513 contacts (-55.9/contact) + 2D Compatibility (PS) -44684 + (NN) -23670 + (LL) 928 1D Compatibility (HY) -33200 + (ID) 9650 Total energy: -306618.0 ( -87.28 by residue) QMean score : 0.458

(partial model without unconserved sides chains): PDB file : Tito_2DVM.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2DVM-query.scw PDB file : Tito_Scwrl_2DVM.pdb: