Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKLDEFTIGQVFKTKSLKVSKDDIMRFAGE-FDPQYMHVDEEKASKGRFNGIIASGIQTLAISFKLWIEEG--FY-GDDIIAGTEMNHMTFIKPVYPDDELFTIVEVLDKQPKRNELGILTVLLSTYNQKEVKVFEGELSVLIKR 1Q6W Chain:A ((14-157)) -YFESIQIGEKIEGLPRTVTETDIWTFAYLTADFFPLHTDVEFAKKTIFGKPIAQGMLVLSIALGMVDQVILSNYDVSSVIAFFGIKDVRFLRPVFIGDTIAASAEVVEKQDFDEKSGVVTYKLEVKNQRGELVLTALYSALIRK

General information: TITO was launched using: RESULT: Template: 1Q6W.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 637 -75763 -118.94 -541.16 target 2D structure prediction score : 0.49 Monomeric hydrophicity matching model chain A : 0.72 3D Compatibility (PKB) : -118.94 2D Compatibility (Sec. Struct. Predict.) : 0.49 1D Compatibility (Hydrophobicity) : 0.72 QMean score : 0.295

(partial model without unconserved sides chains): PDB file : Tito_1Q6W.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1Q6W-query.scw PDB file : Tito_Scwrl_1Q6W.pdb: