Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MVTIKKDFIPVSNDNRPGYAMAPAYITVHNTANTAKGADAKMHAKFVKNPNTSESWHFTVDDSVIYQHLPIDENGWHAGDGTNGTGNRKSIGIEICENADG--DFEKATSNAQWLIRKLMKENNIPLNRVVPHKKWSGKECPRKLL--DHWNSFLNGISSSDTPPKETSPSYPLPSGVIKLTSPYRKGTNILQLQKALAVLHFYPDKGAKNNGIDGVYGPKTANAVKRFQLMNGLTADGIYGPKTKAKLKSKLK 1YB0 Chain:C ((1-157)) MEIRKKLVVPSKYGTKCPYTMKPKYITVHNTYNDAP---AENEVNYMITNNNEVSFHVAVDDKQAIQGIPWERNAWACGDG-NGPGNRESISVEICYSKSGGDRYYKAENNAVDVVRQLMSMYNIPIENVRTHQSWSGKYCPHRMLAEGRWGAFIQKVKSG---------------------------------------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 1YB0.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain C - contact count / total energy / energy per contact / energy per residue : 845 1136 1.34 7.42 target 2D structure prediction score : 0.73 Monomeric hydrophicity matching model chain C : 0.69 3D Compatibility (PKB) : 1.34 2D Compatibility (Sec. Struct. Predict.) : 0.73 1D Compatibility (Hydrophobicity) : 0.69 QMean score : 0.473

(partial model without unconserved sides chains): PDB file : Tito_1YB0.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1YB0-query.scw PDB file : Tito_Scwrl_1YB0.pdb: