Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MFQTLDHFLKSWEFEADATQKLLNSLTDESLKQEITSQNWTLGRIAWHTVAAIGI-ITSNTD---LT---FQAPA---E---DYPVPTSAQFIADSYHQASNAFVQALKTQWTDHTLQERINFI--GQQMPNGSLLMFLIQHQNHHRGQMTVLMRQAGLTVPGIYGPAKEEWAKFGLEAPKM 1RXQ Chain:A ((22-177)) --EQKDKWIQVLEEVPAKLKQAVEVMTDSQLDTPYRDGGWTVRQVVHHLADSHMNSYIRFKLSLTEETPAIRPYDEKAWSELKDSKTADPSGSLALLQELHGRWTALLRTL-TDQQFKRGFYHPDTKEIITLENALGLYVWHSHHHIAHITELSRRMGW-----------------------

General information: TITO was launched using: RESULT: Template: 1RXQ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 498 -12646 -25.39 -89.68 target 2D structure prediction score : 0.52 Monomeric hydrophicity matching model chain A : 0.63 3D Compatibility (PKB) : -25.39 2D Compatibility (Sec. Struct. Predict.) : 0.52 1D Compatibility (Hydrophobicity) : 0.63 QMean score : 0.572

(partial model without unconserved sides chains): PDB file : Tito_1RXQ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1RXQ-query.scw PDB file : Tito_Scwrl_1RXQ.pdb: