Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MLTKPLQGPPAPPGTPTPPPGGKDREAFEAEYRLGPLLGKGGFGTVFAGHRLTDRLQVAIKVIPRNRVLGWSPLSDSVTCPLEVALLWKVGAGGGHPGVIRLLDWFETQEGFMLVLERPLPAQDLFDYITEKGPLGEGPSRCFFGQVVAAIQHCHSRGVVHRDIKDENILIDLRRGCAKLIDFGSGALLHDEPYTDFDGTRVYSPPEWISRHQYHALPATVWSLGILLYDMVCGDIPFERDQEILEAELHFPAHVSPDCCALIRRCLAPKPSSRPSLEEILLDPWMQT---PAEDVPLN--PSKGGPAPLAWSLLP 4ENX Chain:A ((10-278)) ------------------------------QYQVGPLLGSGGFGSVYSGIRVSDNLPVAIKHVEKDRISDWGEL---TRVPMEVVLLKKVSSG--FSGVIRLLDWFERPDSFVLILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHNCGVLHRDIKDENILIDLNRGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDIPFEHDEEIIRGQVFFRQRVSSECQHLIRWCLALRPSDRPTFEEIQNHPWMQDVLLPQETAEIHLH---------------

General information: TITO was launched using: RESULT: Template: 4ENX.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -180866 for 2126 contacts (-85.1/contact) + 2D Compatibility (PS) -27724 + (NN) -13565 + (LL) -624 1D Compatibility (HY) -30800 + (ID) 8050 Total energy: -261629.0 ( -123.06 by residue) QMean score : 0.483

(partial model without unconserved sides chains): PDB file : Tito_4ENX.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4ENX-query.scw PDB file : Tito_Scwrl_4ENX.pdb: