Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MAAQTDYKKQVVGILL--SLAFVLFVFSFS------ERHEKPLVEGKKQENWHTVVDKASVKIY-----------GSRLVEENKLKQ--------KLGHKQADSILTLLKLANEKH-ITL----- 2AI6 Chain:A ((1-125)) MAVADLALIPDVDIDSDGVFKYVLIRVHSAPRSGAPAAESKEIVRGYKWAEYHADIYDKVSGDMQKQGCDCECLGGGRISHQSQDKKIHVYGYSMAYGPAQHAISTEKIKAKYPDYEVTWANDGY

General information: TITO was launched using: RESULT: Template: 2AI6.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 365 -27995 -76.70 -304.29 target 2D structure prediction score : 0.28 Monomeric hydrophicity matching model chain A : 0.63 3D Compatibility (PKB) : -76.70 2D Compatibility (Sec. Struct. Predict.) : 0.28 1D Compatibility (Hydrophobicity) : 0.63 QMean score : 0.254

(partial model without unconserved sides chains): PDB file : Tito_2AI6.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2AI6-query.scw PDB file : Tito_Scwrl_2AI6.pdb: