Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKLYMSVDMEGISGLPDDTFVDSGKRNYERGRLIMTEEANYCIAEAFNSGCTEVLVNDSHSKMNNLMVEKLHPEADLISGDVKPFSMVEGLDDTFRGALFLGYHARAST-PGVMSHSMIFGVRHFYINDRPVGELGLNAYVAGYYDVPVLMVAGDDRAAKEAEELI-PNVTTAAVKQTISRSAVKCLSPAKAGRLLTEKTAFALQNKDKVKPLTPPDRPVLSIEFANYGQAEWANLMPGTEIKTGTTTVQFQAKDMLEAYQAMLVMTELAMRTSFC 1Q6Z Chain:A ((5-148)) --------------------------------------HGTTYELLRRQGIDTVFGNPGSN--ALPFLKDFPEDFRY----------ILALQEACVVGIADGYAQASRKPAFINLHSAAG-TGN-AMGAL---------SNAWNSHSPLIVTAGQQTRAMIGVEALLTNVDAANLPRPLVKWSYEPASAAEVPHAMSRAIHMASM-----------------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 1Q6Z.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 632 -55194 -87.33 -388.69 target 2D structure prediction score : 0.40 Monomeric hydrophicity matching model chain A : 0.59 3D Compatibility (PKB) : -87.33 2D Compatibility (Sec. Struct. Predict.) : 0.40 1D Compatibility (Hydrophobicity) : 0.59 QMean score : 0.251

(partial model without unconserved sides chains): PDB file : Tito_1Q6Z.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1Q6Z-query.scw PDB file : Tito_Scwrl_1Q6Z.pdb: