Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MANFIEKITYLGTPAIKAGNEHLEMIVVPEWGSNVISLVDKTTNVQLLREPET---AESFHDTPTLYGIPILFPPNRISDGTFSFRGRTYHFDINEKDKHNHLHGFLYHEKWNVVTTKQTDEGV--IVETEIDLSELPHVQKQFPHHAVVRMTYTIKENTLFKHATVMNKGKEAFPWGIGYHTTFIFPA------ESSLFSLTADQQWELDERLLPTGKLMDVPYK-EALH-EGMDLRHKQLDDVFLSSYQKRGG--ENQAVIYHQHAHISIIYKADEQFKHWVVYNADGKQGYLCPEPYTWVTNAVNLDLPSSLTGLQVLEPGEETTAKSSITIELNHQ 3OS7 Chain:A ((12-339)) ------EIIWSEHKCIRFAAGGYEALIIPDVGGNVVELKDTNKGVTILRTPKKDLKFEDFKNRPQVYGLPVLFPPNRIDDGTFKLGDKTYKFPINEAKNNNYIHGFIKNSKWTVHKKKIDQDKALVEVVFDFTKEN--EAYKYFSHEFQFKLSYELSSKGLKQTTSVVNLSSEEMPLSVGYHSAFNVPFIEGSEDSNCRVKISIDKFWKQDSRNLPTGESFAPTGEQKEYLENGVAVASHPIESLFSLKDIDVNGKTFRGACIEDASKNTRVVYEMSSEYKYLVIWNDMGDKKYACIEPQTSIINSPNVKLDRSVSGFKTLKPNESWSGVCKLYIE----

General information: TITO was launched using: RESULT: Template: 3OS7.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1751 74578 42.59 238.27 target 2D structure prediction score : 0.53 Monomeric hydrophicity matching model chain A : 0.75 3D Compatibility (PKB) : 42.59 2D Compatibility (Sec. Struct. Predict.) : 0.53 1D Compatibility (Hydrophobicity) : 0.75 QMean score : 0.447

(partial model without unconserved sides chains): PDB file : Tito_3OS7.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3OS7-query.scw PDB file : Tito_Scwrl_3OS7.pdb: