Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKVIKGLTAGLIFLFLCACGGQQIKDPLNYEVEPFTFQNQDGKNVSLESLKGEVWLADFIFTNCETICPPMTAHMTDLQKKLKAENIDVRIISFSVDPENDKPKQLKKFAANYPLSFDNWDFLTGYSQSEIEEFALKSFKAIVKKPEGEDQVIHQSSFYLVGPDGKVLKDYNGVENTPYDDIISDVKSASTLK 4NMU Chain:A ((8-146)) ------------------------KMQIGKEAPNFVVTDLEGKKIELKDLKGKGVFLNFWGTWCK-PCEKEMPYMNELYPKYKEKG--VEIIALDADE---TDIAVKNFVNQYGL---KFPVAIDK--G--QKIIGT-YGVGPLP-----------TSFLIDKDGKVVEQIIGEQ--TKEQLEGYLKKIT---

General information: TITO was launched using: RESULT: Template: 4NMU.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 682 -70131 -102.83 -504.54 target 2D structure prediction score : 0.72 Monomeric hydrophicity matching model chain A : 0.67 3D Compatibility (PKB) : -102.83 2D Compatibility (Sec. Struct. Predict.) : 0.72 1D Compatibility (Hydrophobicity) : 0.67 QMean score : 0.592

(partial model without unconserved sides chains): PDB file : Tito_4NMU.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4NMU-query.scw PDB file : Tito_Scwrl_4NMU.pdb: