Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MPTEIYVDGASAGNPGPSGIGIFIKHE--GKAESFSIPIGVHTNQEAEFLALIEGMKLCATRGYQ----SVSFRTDSDIVERATE-LEMVKNITFQPFVEEIIRLKAA-FPLFFIKWIPGKQNQKADLLAKEAIRLNEKN 4H8K Chain:B ((6-135)) ----IYTDGGARGNPGPAGIGVVITDEKGNTLHESSAYIGETTNNVAEYEALIRALEDLQMFGDKLVDMEVEVRMNSELIVRQMQGVYKVKEPTLKEKFAKIAHIKMERVPNLVFVHIPREKNARADELVNEAI------

General information: TITO was launched using: RESULT: Template: 4H8K.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 549 -14919 -27.17 -122.28 target 2D structure prediction score : 0.65 Monomeric hydrophicity matching model chain B : 0.75 3D Compatibility (PKB) : -27.17 2D Compatibility (Sec. Struct. Predict.) : 0.65 1D Compatibility (Hydrophobicity) : 0.75 QMean score : 0.477

(partial model without unconserved sides chains): PDB file : Tito_4H8K.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4H8K-query.scw PDB file : Tito_Scwrl_4H8K.pdb: