Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKIRGLDQFIQSLDRASRGGLKRKYEQWLESMGFEFLDIIQDEIIRTKTVDTRRLLNSFQKGDQDNIFSMTEGSLKLDVGTNLDYASYVNDGHFTIDPSKNQDRRWVPGRWKGDRFEYDPAEKNSGMLLKFRWVDGSGFWDNAMAIFQLMFERSLERKLQQWIYEEF 4B7Y Chain:C ((1-115)) MNPVNATALYISASRLVLNY---------------------------------------DPGDPKAFTEINRLLPYFRQSLSCCVCGHLLQDPIA--PTNSTCQHYVCKTCKGKKMMMKPSCSWCKDYEQFEE-------NKQLSILVNCYKKLCEYITQTTL----

General information: TITO was launched using: RESULT: Template: 4B7Y.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain C - contact count / total energy / energy per contact / energy per residue : 415 -35406 -85.32 -307.88 target 2D structure prediction score : 0.69 Monomeric hydrophicity matching model chain C : 0.62 3D Compatibility (PKB) : -85.32 2D Compatibility (Sec. Struct. Predict.) : 0.69 1D Compatibility (Hydrophobicity) : 0.62 QMean score : 0.305

(partial model without unconserved sides chains): PDB file : Tito_4B7Y.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4B7Y-query.scw PDB file : Tito_Scwrl_4B7Y.pdb: