Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNIAQVAKQFGLTAATLRYYERVGLIPPVKRKDSGIRDYDEEDIKWIEFIKCMRNAGLSIEALIEYTTLFTEGDRTVEARKNILADERQRLIEKRKEIDETIKRLDTKIKDYDGKLRENEAKLKSRPKTESLHGSVEQRR 1Q06 Chain:B ((1-100)) MNISDVAKITGLTSKAIRFYEEKGLVTPPMRSENGYRTYTQQHLNELTLLRQARQVGFNLEESGELVNLFNDPQ-HS-------ADVKRRTLEKVAEIERHIEELQS---------------------------------

General information: TITO was launched using: RESULT: Template: 1Q06.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 286 -37837 -132.30 -382.19 target 2D structure prediction score : 0.81 Monomeric hydrophicity matching model chain B : 0.79 3D Compatibility (PKB) : -132.30 2D Compatibility (Sec. Struct. Predict.) : 0.81 1D Compatibility (Hydrophobicity) : 0.79 QMean score : 0.649

(partial model without unconserved sides chains): PDB file : Tito_1Q06.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1Q06-query.scw PDB file : Tito_Scwrl_1Q06.pdb: