Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKTYKGYLIDLDGTMYNGTEKIEEACEFVRTLKDRGVPYLFVTNNSSRTPKQVADKLVSFDIPATEEQVFTTSMATAQHIAQQKKDASVYVIGEEGIRQAIEENGLTF-GGENADFVVVGIDRSITYEKFAVGCLAIRNGARFISTNGDIAIPTERGLLPGNGSLTSVLTVSTGVQP-VFIGKPESIIMEQAMRVLGTDVSETLMVGDNYATDIMAGINAGMDTLLVHTGVTKREHMTDDME----KPTHAIDSLTEWIPYI 4JDP Chain:B ((24-282)) MPDKKGYIIDIDGVIGKSVTPIPEGVEGVKKLKELGKKIIFVSNNSTRSRRILLERLRSFGLEVGEDEILVATYATARFIAREKPNAKVFTTGEEGLIEELRLAGLEIVDYDEAEYLVVGSNRKINFELMTKALRACLRGIRYIATNPDRIFPAEDGPIPGTGMIIGALYWMTGREPDVVVGKPSEVIMREALDILGLDAKDVAVVGDQIDVDVAAGKAIGAETVLVLTGVTTRENLDQMIERHGLKPDYVFNSLKDMV---

General information: TITO was launched using: RESULT: Template: 4JDP.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 1470 -58169 -39.57 -229.92 target 2D structure prediction score : 0.68 Monomeric hydrophicity matching model chain B : 0.80 3D Compatibility (PKB) : -39.57 2D Compatibility (Sec. Struct. Predict.) : 0.68 1D Compatibility (Hydrophobicity) : 0.80 QMean score : 0.592

(partial model without unconserved sides chains): PDB file : Tito_4JDP.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4JDP-query.scw PDB file : Tito_Scwrl_4JDP.pdb: