Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MDYRRDGQNDQHQTEPSHTEQQNTENQKLIGHSEQELLDAPVSYEAGRQETASALEMEKQETAVKKEKKRRAAWLSPILGGIIGGGLMLGIAPYLPSDQNQATETASANKQVQSDNFTTAPITNASNIADMVEDLEPTIVGISNIQTSQNNTFGTGGGSSSESESGTGSGVIFKKDSDKAYIITNNHVVEGANKLTVTLYNGETETAKLVGSDTITDLAVLEISGKNVKKVASFGDSSQLRTGEKVIAIGNPLGQQFSG--TVTQGIISGLNRTIDVDTTQGTVEMNVLQTDAAINPGNSGGPLINASGQVIGINSLKVSESGVE-SLGFAIPSNDVEPIVDQLLQNGKVDRPFLGVQMIDMSQVPETYQENTLGLFGDQLGKGVYVKEVQANSPAEKAGIKSEDVIVKLNGKDVESSADIRQILYKDLKVGDKTTIQVLRKGKTKTLNATLTKQTESSSS 3PV3 Chain:D ((79-351)) -----------------------------------------------------------------------------------------------------------------------------------------------------------------------GSGVII--DPNNGVIITNDHVIRNASLITVTLQDGRRLKARLIGGDSETDLAVLKIDAKNLKSLV-IGDSDKLEVGDFVVAIGNPFGLN---SQSATFGIVSALK--------------NFIQTDAAINPGNAGGALVNAKGELIGINTAILS-YGGNVGIGFAIPINMVKDVAQQIIKFGSIHRGLMGIFVQHLT--PELAQ--AMGYPEDF--QGALVSQVNPNSPAELAGLKAGDIITQINDTKITQATQVKTTISL-LRVGSTVKIIVERDNKPLTLSAVVT--------

General information: TITO was launched using: RESULT: Template: 3PV3.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain D - contact count / total energy / energy per contact / energy per residue : 1374 -35715 -25.99 -140.06 target 2D structure prediction score : 0.59 Monomeric hydrophicity matching model chain D : 0.74 3D Compatibility (PKB) : -25.99 2D Compatibility (Sec. Struct. Predict.) : 0.59 1D Compatibility (Hydrophobicity) : 0.74 QMean score : 0.522

(partial model without unconserved sides chains): PDB file : Tito_3PV3.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3PV3-query.scw PDB file : Tito_Scwrl_3PV3.pdb: