Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MDIIFVCTGNTCRSPMAEALFKSIAEREGL--NVNVRSAGVFASPNGKAT-PHAVEALFEKHIALNHVSSPLTEELMESADLVLAMTHQHKQIIASQFGRYRDKVFTLKEYVTGSHGDVLDPFGGSIDIYKQTRDELEELLRQLAKQLKKDRR 2CWD Chain:C ((7-143)) --VLFVCLGNICRSPMAEGIFRKLLKERGLEDRFEVDSAGTGAWHVGEPMDPRARRVLEEEGAYFPHVARRLTREDVLAYDHILVMDRENLEEVLRRFPEARGKVRLVLEELGG--GEVQDPYYGDLEDFREVYWTLEAAL------------

General information: TITO was launched using: RESULT: Template: 2CWD.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain C - contact count / total energy / energy per contact / energy per residue : 681 -9713 -14.26 -72.48 target 2D structure prediction score : 0.67 Monomeric hydrophicity matching model chain C : 0.78 3D Compatibility (PKB) : -14.26 2D Compatibility (Sec. Struct. Predict.) : 0.67 1D Compatibility (Hydrophobicity) : 0.78 QMean score : 0.528

(partial model without unconserved sides chains): PDB file : Tito_2CWD.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2CWD-query.scw PDB file : Tito_Scwrl_2CWD.pdb: