Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEPKRSRLVV---------------CAPEPSHAREFPDVAVFSGGRANASQAERLARAVGRVLADRGVTGGARVRLTMANCADGPTLVQINLQVGDTPLRAQAATAGIDDLRPALIRLDR------QIVRASAQWCPRPWPDRPRRRLTTPAEALVTRRKPVVLRRATPLQAIAAMDAMDYDVHLFTDAETGEDAVVYRAGPSGLRLARQHHVFPPGWSRCRAPAGPPVPLIVNSRPTPVLTEAAAVDRAREHGLPFLFFTDQATGRGQLLYSRYDGNLGLITPTGDGVADGLA 2FZV Chain:A ((23-257)) NAMRLRHLSDPDSLPALDKSFAIERPALGLAPDAPPVRILLLYGSLRARSFSRLAVEEAARLLQFFGA------ETRIFDPSDLPLP---DQVQSDDHPAVKELRALSEWSEGQVWCSPERHGQITSVMKAQIDHLPLEMAGIR-----------PTQGRTLAVMQVSGGSQSFNAVNTLRLLGRWMRMFTIPNQSSIAKAFQEFD------------------------------AAGRMKPSPYYDRIADVMEELVRFTALVRPHREALTDRYSERKAAGHVI---------

General information: TITO was launched using: RESULT: Template: 2FZV.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -52969 for 1716 contacts (-30.9/contact) + 2D Compatibility (PS) -23310 + (NN) -17549 + (LL) 2852 1D Compatibility (HY) 4000 + (ID) 1100 Total energy: -88076.0 ( -51.33 by residue) QMean score : 0.160

(partial model without unconserved sides chains): PDB file : Tito_2FZV.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2FZV-query.scw PDB file : Tito_Scwrl_2FZV.pdb: