Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTVVPGAPSRPASAVSRPSYRQCVQASAQTSARRYSFPSYRRPPAEKLVFPVLLGILTLLLSACQTASASGYNEPRGYDRATLKLVFSMDLGMCLNRFTYDSKLAPSRPQVVACDSREARIRNDGFHANAPSCMRIDYELITQNHRAYYCLKYLVRVGYCYPAVTTPGKPPSVLLYAPSACDESLPSPRVATALV------PGTRSANREFSRFVVTEIKSLGAGGRCDSASVSLQPPEEIEGPAIPPASSQLVCVAPK 1D4V Chain:B ((119-281)) ----P---QRVAAHITGTRGRS------------------------------------------NTLSSPNSKNEKALGRKINSWESS--------------------------RSGHSFLSN--LHLR-NGELVI-------HEKGFYYIYSQTYFRFQEEIKENTKNDKQMVQYIYKYTS-YPDPILLMKSARNSCWSK----DAEYGLYSIYQGGIFELKEN---DRIFVSVTNEHLIDM---DHEASFFGAFLVG

General information: TITO was launched using: RESULT: Template: 1D4V.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -42269 for 1170 contacts (-36.1/contact) + 2D Compatibility (PS) -16349 + (NN) -4387 + (LL) 6160 1D Compatibility (HY) -2800 + (ID) 1100 Total energy: -60745.0 ( -51.92 by residue) QMean score : 0.148

(partial model without unconserved sides chains): PDB file : Tito_1D4V.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1D4V-query.scw PDB file : Tito_Scwrl_1D4V.pdb: