Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTAQLIDGKAIAANLRQQIAQRVT--ERRQQGLRVPGLAVILVGTDPASQVYVAHKRKDCEEVGFLSQAYDLPAETSQDDLLALIDRLNDDPAIDGILVQLPLPAHLDASLLLERIHPDKDVDGFHPYNIGRL--AQRMPLLRPCTPKGIMTLLASTGADLYGMDAVVVGASNIVGRPMALELLLGGCTVTVTHRFTR--DLADHVSRADLVVVAAGKPGLVKGEWIKEGAIVIDVGINRQADG------RLVGDVEYEVAAQRASWITPVPGGVGPMTRACLLENTLHAAEHLHD 4CJX Chain:B ((25-309)) --AVVIDGRAVAKAIQKELTEEVALLERRYKGRR-PGLSTIICGKRKDSQTYVRLKRKAAAACGFRNFSVELPANVTQEALEREVIRLNEEEACHSIVVQLPLPPHIDKVAALSKIKPEKDADCLLPVNVGQLHIRERNPAIVPCTASAVMELLRCSGVEICGKRVVVLGRGDIAGLPVATLLANEDATVTVVHSATPLCDIADIVRASDIVVSAAGQPGLVRGEWIKLGAAVIDVGTTPVADPSKVPGYRLVGDVCFDVARKRAAYITPVPGGVGPVTVSMLLKNTLTMFKRSVR

General information: TITO was launched using: RESULT: Template: 4CJX.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -207244 for 2354 contacts (-88.0/contact) + 2D Compatibility (PS) -29829 + (NN) -14259 + (LL) 452 1D Compatibility (HY) -20800 + (ID) 6600 Total energy: -278280.0 ( -118.22 by residue) QMean score : 0.578

(partial model without unconserved sides chains): PDB file : Tito_4CJX.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4CJX-query.scw PDB file : Tito_Scwrl_4CJX.pdb: