Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKQIMIFLTSFMLLAMTGQTALAKDVQVSGSLLGKSSQEQAKQQVLTSELITLYGSKDSAELTYQIPAGASSGNQQLVIEYEASNLLISPSSLTVVIDDEPVKTLKLDGDSKRKTVKLNLNKSQSAQGYHNVSLKFYGVMKEGVCVRQDTSGNWIKIYPDSRLTLADSSEAKGTSLDHYPYPFAQSGNTAEETAIVIPDNPSSAEIEAAVKTEGYLKTVDSSVSIAYVTESELKKIDKPTIVIGVDKHWNGKVKKLLKQAGLQAKGENLLLAERVLKAEGKQQPVLFAQAASEDALTKKISVMTDQTYTGQLSGDTLSISKLQQTEKKESDKLTLENFGAGDITIGADKTSSAHYFYPASAVLDENQSAKLSLKLKKSETIQASTAENESASQAAELK-VMINGQPHSVRLDELGKEDKNGF-YHVTVKVDPKLLQKNRYIDIQFVTTGLKENNPCNTTDEEKWVFIDKNSTLSYAIKGMSPSADFQEWPLPYAGNQDQTTLIVLPDTVSQSKLEELSLVTESFGNEAQHSYTVKKSSDVTANDAKGRNLIFI----GGINQFSLLKEK---SSDLLVPQEKNGSFDVSSFEMLNE----TTKQVVFTQASVWDSRYTMAVFAPSKGDGTAVTKEIISYLNSNDESATVLNETNSQQVFTNHQQLKSETNSSDAEQPTQDHSQKWMYIGVLALIMVVAAVFIWIAVRRKKRKTDTE---- 4FXK Chain:A ((1-651)) --KPRLLLFSPSVVHLGVPLSVGVQLQ-------DVPRGQVVKGSVFLRNPSRNNVPCSPKVDFTLSSERD------------------FALLSLQVPLKDAKSCGLHQLLRGPEVQLVAHSPWLKDSLSRTTNI------QGINLLFSSRRGHLFLQTDQPIY------NPGQRVRYRVFALDQKMRPSTDTITVMVENSHG------LRVRKKEVYMPSSIFQDDFVIPDISEPGTWKISARFSDGLESNSS-----TQFEVKKYVLPNFEVKITPG---KPYILTVPGHLDEM--QLDIQARYIYGKPVQG----VAYVRFGLLDEDGKKTFFRGLESQTKLVNGQSHISLSKAEFQDALEKLNMGITDLQGLRLYVAAAIIESPGGEMEEAELTSWYFVSSPFSLDLSKTKRHLVPGAPFLLQALVREMSGSPASGIPVKVSATVSSPGSVPEVQDIQQNTDGSGQVSIP-----IIIPQTISELQLSVSAGSPHPAIARLTVAAPPSGGPGFLSIERPDSRPPRVGDTLNLNLRAVGSGATFSHYYYMILSRGQIVFMNREPKRTLTSVSVFVDHHLAPSFYFVAFYYHGDHPVANSLRVDVQAGACEGKLELSVDGAKQYRNGESVKLHLET-----DSLALVALGALDTALYAAGSKSHKPLNMGKVFEAMNSYDLGCGPGGGDSALQVFQAAGLAFSDGDQWTLSRKRLSCP

General information: TITO was launched using: RESULT: Template: 4FXK.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 3143 -127553 -40.58 -201.19 target 2D structure prediction score : 0.40 Monomeric hydrophicity matching model chain A : 0.64 3D Compatibility (PKB) : -40.58 2D Compatibility (Sec. Struct. Predict.) : 0.40 1D Compatibility (Hydrophobicity) : 0.64 QMean score : 0.086

(partial model without unconserved sides chains): PDB file : Tito_4FXK.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4FXK-query.scw PDB file : Tito_Scwrl_4FXK.pdb: