Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MAQEKAVIRDPKKLNAFDLRWIASLFGTAVGAGILFLPIRAGGHGIWAIVVMSAIIFPLTYLGHRALAYFIGSKDKEDITMVVRSHFGAQWGFLITLLYFLAIYPICLAYGVGITNVFDHFFTNQLHLAPFHRGLLAVALVSLMMLVMVFNATIVTRICNALVYP-LCLILLLFSLYLIPYWQGANLFVVPSFKEFVLAIWLTLPVLVFSFNHSPIISTFTQNVGKEYGAFKEYKLNQIELGTSLMLLGFVMFFVFSCVMCLNADDFVKAREQNIPILSYFANTLNNPLINYAGPVVAFLAIFSSFFGHYYGAKEGLEGIIIQS-LKLKQASKTLSVGVTIFLWLTITLVAYINPNILDFIENLGGPIIALILFVMPMIAFYSVSSLKRFRNFKVDIFVFVFGSLTALSVFLGLF 4KRT Chain:A ((7-353)) HHHHHMQSRNNNNLKGIDV--------SNWKGNINFESVKNDGVEVVYIKATEGNYFKDKY----AKQNYEGAKEQ-GLSVGFYHFFRANKGAKDQANFFIDYLNEIGAVNYDCKLALDIETTEGVG----VRDLTSMCIEFLEEVKRLTGKEVVVYTYTSFANNNLDSRLGNYPVWIAHY--GVNTPGANNIWSSWVGFQYSENGSVAGVNGGCDMNEFTEEIFIDSSNFNLDNATTKNVSTKLNIR--------------------AKGTTNSKIIGSIP----------AGETFKIKWVDEDYLGWYYVEYNGVVGYVNADYVEKLQMATTYNVST----FLNVREEGSLNSRIVDKINS--GDIFRIDWVDSDFIGWYRITTKNGKVGFVNAEFVKKL-------------

General information: TITO was launched using: RESULT: Template: 4KRT.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -389801 for 2709 contacts (-143.9/contact) + 2D Compatibility (PS) -35655 + (NN) 7642 + (LL) 5160 1D Compatibility (HY) -7200 + (ID) 2950 Total energy: -422804.0 ( -156.07 by residue) QMean score : 0.155

(partial model without unconserved sides chains): PDB file : Tito_4KRT.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4KRT-query.scw PDB file : Tito_Scwrl_4KRT.pdb: