Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MLENRVKTKQIFIGGVAIGGDAPISTQSMTFSKTADIESTKNQIDRFKLAGADLVRVAVSNEKDALALKELKKV-----SPLPLIADIHFHYKFALIA----AQSVDAIRINPGNIG---SKDK-----IKAVVDACKEKNIPIRIGVNAGSLEKQF-----DQKYG-PTPK--------GMVESAL--YNAKLLEDLDFTDFKISLKASDVVRTIEAYRMLRPLVIYPFHLGVTEAGNLFSSSIKSAMALGGLLMEGIGDTMRVSITGELEN----EIKVARAILRHSGRLKEGINWISCPTCGRIEANLV-DMASKVEKRLS------HIKTP----LDISVMGCVVNALGEAKHADMAIAFGNRS----GLIIKEGKVIHKLAEKDLFETFVIEVENLAKEREKSLKD 4S23 Chain:B ((5-401)) ----RRPTPTVYVGRVPIGGAHPIAVQSMTNTPTRDVEATTAQVLELHRAGSEIVRLTVNDEEAAKAVPEIKRRLLAEGVEVPLVGDFHFNGHLLLRKYPKMAEALDKFRINPGTLGRGRHKDEHFAEMIRIAMDLGK----PVRIGANWGSLDPALLTELMDRNASRPEPKSAHEVVLEALVESAVRAYEAALEMGLGEDKLVLSAKVSKARDLVWVYRELARRTQAPLHLGLTEAGMGVKGIVASAAALAPLLLEGIGDTIRVSLTPSPKEPRTKEVEVAQEILQALGLRAFAPEVTSCPGCGRTTSTFFQELAEEVSRRLKERLPEWRARYPGVEELKVAVMGCVVNGPGESKHAHIGISLPGAGEEPKAPVYADGKLLTILKGEGIAEEFLRLVEDYVKTRFAPKA-

General information: TITO was launched using: RESULT: Template: 4S23.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -158823 for 2772 contacts (-57.3/contact) + 2D Compatibility (PS) -37847 + (NN) -24445 + (LL) 804 1D Compatibility (HY) -22400 + (ID) 6850 Total energy: -249561.0 ( -90.03 by residue) QMean score : 0.508

(partial model without unconserved sides chains): PDB file : Tito_4S23.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4S23-query.scw PDB file : Tito_Scwrl_4S23.pdb: