Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSVLEIKNLHVSIEDKEILKGLNLTLKTGEIAAIMGPNGTGKSTLSAAIMGNPNYEVTAGEILFDGEDILELEVDE-RARLG-------LFLA-----MQYPSEVPGITNAEFIRAAMNAGKADDDKISIRQFITKLDEKMELLGMKEEMAERYLNEG--FSGGEKKRNEILQLLMLEPKFALLDEIDSGLDIDALKVVSKGVNEMRGEGFGAMIITHYQRLLNYITPDKVHVMMDGKVVLSGGPELAVRLEKEGYAQIAEELGLEYKEEV 4M1M Chain:B ((1048-1247)) -----------------VLQGLSLEVKKGQTLALVGSSGCGKSTVVQLL--ERFYDPMAGSVFLDGKEIKQLNVQWLRAQLGIVSQEPILFDCSIAENIAYGDNSRVVSYEEIVRAAKEA--------NIHQFIDSLPDKYN---------TRVGDKGTQLSGGQKQRIAIARALVRQPHILLLDEATSALDTESEKVVQEALDKAR-EGRTCIVIAH--RLSTIQNADLIVVIQNGKVKEHGTHQQLLAQKGIYFSMVSVQA--------

General information: TITO was launched using: RESULT: Template: 4M1M.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -65622 for 1268 contacts (-51.8/contact) + 2D Compatibility (PS) -19869 + (NN) -6619 + (LL) 2924 1D Compatibility (HY) -12800 + (ID) 3550 Total energy: -105536.0 ( -83.23 by residue) QMean score : 0.420

(partial model without unconserved sides chains): PDB file : Tito_4M1M.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4M1M-query.scw PDB file : Tito_Scwrl_4M1M.pdb: