Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MDYLVKALAYDGKVRAYAARTTDMVNEGQRRHGTWPTASAALGRTMTASLMLGAMLKGDDKLTVKIEGGGPIGAIVADANAKGEVRAYVSNPQVHFDLNEQGKLDVRRAVGTNGTLSVVKDLGLREFFTGQVEIVSGELGDDFTYYLVSSEQVPSSVGVGVLVNPDNTILAAGGFIIQLMPGT-DDETITKIEQRLSQVEPISKLIQKGLTPEEILEEVL-GEKPEILETMPVRFHCPCSKERFETAILGLGKKEIQDMIEEDGQAEAVCHFCNEKYLFTKEELEGLRDQTTR 1VQ0 Chain:A ((14-297)) ---IYYGTMFDHKVRFSIVRMREVVEEARNRHALSYLATVVLGRALIGAALVTPWLAEKERWTLDIEGNGPIRRVVAQSTSEFTVRGYVANPKVELPLNEKGKFDVAGAIGQ-GVLRVVRDLGLKTPFVSQVPLVSGEIAEDLAYYFAVSEQIPSAFSIGVLVDS-DGVKIAGGFAVQIIDRTLEQEKVEMIEKNIKNLPSISKLFQ-EAEPLDVLERIFGE-KVGFVETAEIKYKCDCNREKAKNALLVLDKKELEDMR-KEGKGEVVCKWCNTRYVFSEEELEELLKFKV-

General information: TITO was launched using: RESULT: Template: 1VQ0.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -165380 for 2343 contacts (-70.6/contact) + 2D Compatibility (PS) -30345 + (NN) -5278 + (LL) 440 1D Compatibility (HY) -28400 + (ID) 5500 Total energy: -234463.0 ( -100.07 by residue) QMean score : 0.595

(partial model without unconserved sides chains): PDB file : Tito_1VQ0.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1VQ0-query.scw PDB file : Tito_Scwrl_1VQ0.pdb: