Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKKITTNEQFN-ELIQSDKEIIVKFYADWCPDCTRMNMFIGDILEEYNQN-DWYELNKDELPDLAEKYQVMGIPSLLIFKNGEKTAHLHSANAKTPEEVTEFLSEHIS 2H6Z Chain:B ((8-108)) -----TDDSFDTDVLKADGAILVDFWAEWCGPCKMIAPILDDIADEYQGKLTVAKLNIDQNPGTAPKYGIRGIPTLLLFKNGEVAATKVGALSKG--QLKEFLDANLA

General information: TITO was launched using: RESULT: Template: 2H6Z.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 410 -65412 -159.54 -660.73 target 2D structure prediction score : 0.52 Monomeric hydrophicity matching model chain B : 0.79 3D Compatibility (PKB) : -159.54 2D Compatibility (Sec. Struct. Predict.) : 0.52 1D Compatibility (Hydrophobicity) : 0.79 QMean score : 0.560

(partial model without unconserved sides chains): PDB file : Tito_2H6Z.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2H6Z-query.scw PDB file : Tito_Scwrl_2H6Z.pdb: