Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKYGIVLFPSKKLQDLANSYRKRYDP-SYSLI---PPHLTLRASFECAEEKADQLVSHLRNIAKESHPLVLKMTKYSSFAP--VNNVIY-IKAEPT-EELKTLNEKLYTGVLAG---EQEYNFVPHVTVGQNLSDDEHSDVLGQLKMQEVSHEEIVDRFHLLYQLENGSWTVYETFLLGRGE 4H7W Chain:A ((13-145)) --VYVPYEAKEEFLDLLDVLLPHAQTYVPRLVRMKVFHLSLSQSVVLRHHWILPFVQALKARMTSFHRFFFTANQVKIYTNQEKTRTFIGLEVTSGHAQFLDLVSEVDRVMEEFNLTTFYQDPSFHLSLAWCVGD-----------------------------------------------

General information: TITO was launched using: RESULT: Template: 4H7W.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 392 -66893 -170.64 -548.30 target 2D structure prediction score : 0.67 Monomeric hydrophicity matching model chain A : 0.63 3D Compatibility (PKB) : -170.64 2D Compatibility (Sec. Struct. Predict.) : 0.67 1D Compatibility (Hydrophobicity) : 0.63 QMean score : 0.466

(partial model without unconserved sides chains): PDB file : Tito_4H7W.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4H7W-query.scw PDB file : Tito_Scwrl_4H7W.pdb: