Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNHETFLKRAVTLACEGVNAGIGGPFGAVIVKDGAIIAEGQNNVTTSNDPTAHAEVTAIRKACKVLGAYQLDDCILYTSCEPCPMCLGAIYWARPKAVFYAAEHTDAAEAGFDDSFIYKEIDKPAEERTIPFYQVTLTEHLSPFQAWRNFANKKEY 1WWR Chain:C ((21-133)) MGKEYFLKVALREAKRAFEKG-EVPVGAIIVKEGEIISKAHNSVEELKDPTAHAEMLAIKEACRRLNTKYLEGCELYVTLEPCIMCSYALVLSRIEKVIFSA--LDKKHGGVVSVF----------------------------------------

General information: TITO was launched using: RESULT: Template: 1WWR.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain C - contact count / total energy / energy per contact / energy per residue : 609 -67062 -110.12 -593.47 target 2D structure prediction score : 0.81 Monomeric hydrophicity matching model chain C : 0.75 3D Compatibility (PKB) : -110.12 2D Compatibility (Sec. Struct. Predict.) : 0.81 1D Compatibility (Hydrophobicity) : 0.75 QMean score : 0.463

(partial model without unconserved sides chains): PDB file : Tito_1WWR.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1WWR-query.scw PDB file : Tito_Scwrl_1WWR.pdb: