Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MAKAIQSSMWREFGLMCTVGIGDNMLLSKLALDLESKKTKSGIARWRY--EDVPNRLWKVRPLSKMWGIGGRMERNLNRMGISTVGQLAKFPLELLEKKFGI-MGNQLYYHAHGIDLSEIGAPLMQGQISFGKSQILFRDYTKREEIKAVLLEICEEVARRARTYNKVGRTISLGIGYSKDELGGGFHRSKTIDFPTNITMDIYKCCLMFFNKFYSGKKQ 4U6P Chain:A ((293-496)) VVKEIRFRIEQKTTLTASAGIAPNTMLAKVCSDKNKPN---GQYQILPNRQAVMDFI-KDLPIRKVSGIGKVTEKMLKALGIITCTELYQQR-ALLSLLFSETSWHYFLHISLGLGSTHLTRDG--ERKSMSVERTFSE-INKAEEQYSLCQELCSELAQDLQKERLKGRTVTIKLKNVNFE---VKTRASTVSSVVSTAEEIFAIAKELLKTEI-----

General information: TITO was launched using: RESULT: Template: 4U6P.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 674 -9256 -13.73 -46.05 target 2D structure prediction score : 0.63 Monomeric hydrophicity matching model chain A : 0.69 3D Compatibility (PKB) : -13.73 2D Compatibility (Sec. Struct. Predict.) : 0.63 1D Compatibility (Hydrophobicity) : 0.69 QMean score : 0.471

(partial model without unconserved sides chains): PDB file : Tito_4U6P.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4U6P-query.scw PDB file : Tito_Scwrl_4U6P.pdb: