Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKVIKGLTAGLIFLFLCACGGQQIKDPLNYEVEPFTFQNQDGKNVSLESLKGEVWLADFIFTNCETI-CPPMTAHMTDLQKKLKA----ENIDVRIISFSVDPENDKPKQLKKFAANYPLSFDNWDFLTGYSQSEIEEFALKSFKAIVKKPE----GEDQVIHQSSFYLVGPDGKVLKDYNGVENTPYDDIISDVKSASTLK 2GGT Chain:A ((2-162)) ------------------------------LGGPFSLTTHTGERKTDKDYLGQWLLIYFGFTHCP-DVCPEELEKMIQVVDEIDSITTLPD--LTPLFISIDPERDTKEAIANYVKEFSP---KLVGLTGT-REEVDQVARA-YRVYYSPGPKDEDEDYIVDHTIIMYLIGPDGEFLDYFGQNK--RKGEIAASIATHMRP-

General information: TITO was launched using: RESULT: Template: 2GGT.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 732 30484 41.64 200.55 target 2D structure prediction score : 0.65 Monomeric hydrophicity matching model chain A : 0.67 3D Compatibility (PKB) : 41.64 2D Compatibility (Sec. Struct. Predict.) : 0.65 1D Compatibility (Hydrophobicity) : 0.67 QMean score : 0.675

(partial model without unconserved sides chains): PDB file : Tito_2GGT.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2GGT-query.scw PDB file : Tito_Scwrl_2GGT.pdb: