Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSMAYEEYMRQLVVPMRRELTGAGFEELTTAEEVENFMEKAEGTTLVVVNSVCG-CAAGLARPAATQAVLQNDKTPDNTVTVFAGQDKEATAKMREYFTGQEPSSPSMALLKGKEVVHFIPRHEIEGHDMEEIMKNLTAAFDAHC 2OE3 Chain:A ((7-103)) ---------------------------LTNLTEFRNLIKQNDKLVIDFYATWCGPCKMM--QPHLTK-LI--QAYPD---VRFVKCDVDESPDIAKECE--VTAMPTFVLGKDGQLIGK-----IIGANPTALEKGIKD------

General information: TITO was launched using: RESULT: Template: 2OE3.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 395 -11638 -29.46 -121.23 target 2D structure prediction score : 0.72 Monomeric hydrophicity matching model chain A : 0.66 3D Compatibility (PKB) : -29.46 2D Compatibility (Sec. Struct. Predict.) : 0.72 1D Compatibility (Hydrophobicity) : 0.66 QMean score : 0.628

(partial model without unconserved sides chains): PDB file : Tito_2OE3.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2OE3-query.scw PDB file : Tito_Scwrl_2OE3.pdb: