Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MLEYGFKDDSLSLHTDLYQINMAETYWRDGIHEKKAIFELFFRRLPFENGYAVFAGLEKAIEYLENFKFTDSDLSYLQD-ELGYHEDFIEYLRGLSFTGSLYSMKEGELVFNNEPIM--RVEAPLVEAQLIETALLNIVNYQ---------------TLIATKAARIKGV-----IGDEVALEFGTRRAHEMDA---AMWGARAALIGGFSATSNVRAGKRFNIPVSGTHAHALVQAYR-------DEYTAFKKYAETHKDCVFLVDTYDTLRSGMPNAIRVAKEFGDRINFIGIRLDSGDLAYLSKKARKMLDEAGFT-DAKV-IASSDLDEHTIMNLKAQ--GARIDVWGVGTKLITAYD---------QPALGAVYKLVAIEEDGKMVDTIKISSNPEKVTT--PGRKKVYRIINQSNHHSEGDYIALYDEQVNDQKRLRMFHPVHTFISKFVTNFYAKDLHELIFEKGILCYQNPEISDIQQYVQDNLSLLWEEYKRISKPEEYPVDLSEDCWSNKMQRIHEVKSRIEEELEEE 4HL7 Chain:A ((12-407)) -------IIRSLLDLDAYKINMMQAIHHFYP-DVSVRYELIVRSEEDA--SGLLDAIRQEIAHLGTLRFSDADIHYLTQHAPHLKATFLQSLRYFHFV-PQEQVEMGIVK----QQLRISIRGSWRDTILYETLVMAIVSEVRSRQRWAEVPADLPLKVLKTKLDQLKAEIERRGINNFSLTEMGTRRRFSSQVQRDVLACLKQEIPQWVLGTSNYHFAREFDLKPIGTIAHEWFMGHQALVNERDSQQVALERWLTAFDG-MLAIAPTDTL--TIDAFLNDFNRH-LANAYDGVRHDSGCPFRWGDKMIAHYQQLGIDPTTKLFIFSDGLDFDQALELCEYFAGRVKISFGIGTFLTNDLANWRNAAGVEYRPLSIVIKLAECQG----RPVAKISDQPEKAMCEDPIFLANLK---------------------------------------------------------------------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 4HL7.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1798 -19474 -10.83 -56.61 target 2D structure prediction score : 0.58 Monomeric hydrophicity matching model chain A : 0.66 3D Compatibility (PKB) : -10.83 2D Compatibility (Sec. Struct. Predict.) : 0.58 1D Compatibility (Hydrophobicity) : 0.66 QMean score : 0.425

(partial model without unconserved sides chains): PDB file : Tito_4HL7.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4HL7-query.scw PDB file : Tito_Scwrl_4HL7.pdb: