Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTNNLKQRRIILDLAVTLDGFIEGKNGEVDWCIMD-PD----MGFTDFLNQIDTILYGRKSFDLWGQYIPKNEDPDTEKELWKLVHSKKKYVFSRTQNEI--DNQAIFINDNILEEVNKLKKNPG-KDIWLYGGASLITTFINLGLVDEFRLSIHPVVLGEGKPLFIDVKQRINLKMVNTRTFSSGVVQIVYHWNG 2XW7 Chain:A ((1-174)) ----SHMVKTVYYTASSLDGYIVDENQSLDWLTSRDITPDGPFGYEQFIETIGVLVMGASTYEWVVEHG------------DWSY-DQPAWVLTHRPEIAAESHPMQVFSGDVAELHPELVAAAGGKDVWVVGGGDVAAQFVAADLIDEIIVSYAPCTLGVGSRVLPM---RSEWVLDDCARNGD-FVCARWKRP-

General information: TITO was launched using: RESULT: Template: 2XW7.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 767 -28496 -37.15 -171.66 target 2D structure prediction score : 0.57 Monomeric hydrophicity matching model chain A : 0.71 3D Compatibility (PKB) : -37.15 2D Compatibility (Sec. Struct. Predict.) : 0.57 1D Compatibility (Hydrophobicity) : 0.71 QMean score : 0.436

(partial model without unconserved sides chains): PDB file : Tito_2XW7.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2XW7-query.scw PDB file : Tito_Scwrl_2XW7.pdb: