Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MPSRTALSPGVLSPTRPVPNWIARPEYVGKPAAQEGSEPWVQ--------TPEVIEKMRVAGRIAAGALAEAGKAVAPGVTTDELDRIAHEYLVDNGAYPSTLGYKGFPKSCCTSLNEVICHGIPDSTVITDGDIVNIDVTAYIGGVHGDTNATFPAGDVADEHRLLVDRTREATMRAINTVKPGRALSVIGRVIESYANRFGYNVVRDFTGHGIGTTFHNGLVVLHYDQPAVETIMQPGMTFTIEPMINLGALDYEIWDDGWTVVTKDRKWTAQFEHTLLVTDTGVEILTCL 4U6E Chain:A ((13-292)) -----------LMPTRPVPSYIQRPDYADHPLGMSESEQALKGTSQIKLLSSEDIEGMRLVCRLAREVLDVAAGMIKPGVTTEEIDHAVHLACIARNCYPSPLNYYNFPKSCCTSVNEVICHGIPDRRPLQEGDIVNVDITLYRNGYHGDLNETFFVGEVDDGARKLVQTTYECLMQAIDAVKPGVRYRELGNIIQKHAQANGFSVVRSYCGHGIHKLFHTAPNVPHYAKNKAVGVMKSGHVFTIEPMICEGGWQDETWPDGWTAVTRDGKRSAQFEHTLLVTDTGCEILT--

General information: TITO was launched using: RESULT: Template: 4U6E.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -145588 for 2397 contacts (-60.7/contact) + 2D Compatibility (PS) -29984 + (NN) -14750 + (LL) 596 1D Compatibility (HY) -19600 + (ID) 6850 Total energy: -216176.0 ( -90.19 by residue) QMean score : 0.532

(partial model without unconserved sides chains): PDB file : Tito_4U6E.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4U6E-query.scw PDB file : Tito_Scwrl_4U6E.pdb: