Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MVTVILAEKETQAAAYAESLGPAS-KKGKVHIIKHTPYF-SDEVHVIAAEGHLFEYGLPKD----NWDLDKLPLV----DVSFKQTLKQDKVSKEIFKQIYQEVTAADQVIIGTDSDREGERIAYSILSHIPEGKNKVTKRLWVNSLTTRALQKAFQNLREPIETYNYYLEAEARAQSDWLVGMNLSPLVTLELQKRGRLPKGKGNSLSVGRVQTPGVRLICENDLAIQNFRPETYWKLQLQDKETEISFSNKEKYSDSELILAQARQLKAISIVSSVEMEEKQRAAPHLFNLSDIQGLAAKQWGFEPTKTERLIESLYLKKYLSYPRTDTRFITEEEFDYLKNYLKSYQEVINCSFEAVNLEPRENYVNPEKVAKTSHYALIPTENIPN--L-----------VTLKPDERLIYEAVVRRTLLMFAADCRYSTTTVEVENQGLVFKTTGRQMF----DPGWAAFSQQKLKGDIELPDYRVGDQIETKVIIVEGMTKPPKRITESQLISDILPKYGLGTQATRATMLQTIQDRGYITKDKKTGQLFPTNKAYLLIHYLYDN--EFASPETTGGWELFLSQIGEGEINPREFVDAIKEKLAAQIAVVKERSD 1GKU Chain:B ((506-1054)) -PALFIVESPTKARQISRFFGKPSVKVLDGAVVYEIPMQKYVLM-VTASIGHVVDLITNRGFHGVLVNGRFVPVYASIK---------DNSR--SRIEALRKLAHDAEFVIVGTDPDTEGEKIAWDLKNLLSG--CGAVKRAEFHEVTRRAILEALESLRD--VDENLVKAQVVRRIEDRWIGFVLSQKLWERFN---------NRNLSAGRAQTLVLGWIIDRFQESRERRKIAIVR----------DFDLVLEHDE--E------EFD--LTIKLVEEREELRTPLPPYTTETMLSDANRILKFSVKQTMQIAQELFENGLITYHRTDSTRVSDVGQRIAKEYLGD---DF-----------VGREWGE--S--GAHECIRPTRPLTRDDVQRLIQEGVLVVEGLRWEHFALYDLIFRRFMASQCRPFKVVVKKYSIEFDGKTAEEERIVRAEGRAYELYRAVWVK-----NELP---TGT-FR--VKAEVKSVPKVLPFTQSEIIQMMK-ERGIGRPSTYATIVDRLFMRNYVVEKYG--RMIPTKLGIDVFRFLVRRYAKFVSEDRTRDLESRMDAIERGELDYLKALEDMYAEIKSID--------

General information: TITO was launched using: RESULT: Template: 1GKU.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -135206 for 4037 contacts (-33.5/contact) + 2D Compatibility (PS) -52464 + (NN) -6253 + (LL) 5492 1D Compatibility (HY) -18400 + (ID) 4850 Total energy: -211681.0 ( -52.44 by residue) QMean score : 0.389

(partial model without unconserved sides chains): PDB file : Tito_1GKU.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1GKU-query.scw PDB file : Tito_Scwrl_1GKU.pdb: