Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MIEFVKGTIDYVSPQYIVI-ENGGIGYQIFTPNPFIYKER--SQE-TIFTYHHIREDAFSLYGFSTREEKALFTKLLNVTGIGPKGALAILGSGDPGAVIQAIENEDEAFLVKFPGVGKKTARQIILDLKGKLADVVPEMIENLFNHEERLEKQTAETALEEALEALRVLGYAEKEIKKVLPHLKEE-IGLTTDQYVKKALQKLLK 2ZTD Chain:A ((17-210)) MIASVRGEVLEVALDH-VVIEAAGVGYRVNATPAT-LATLRQGTEARLITAMIVREDSMTLYGFPDGETRDLFLTLLSVSGVGPRLAMAALAVHDAPALRQVLADGNVAALTRVPGIGKRGAERMVLELRDKVG-----------------------AVRSPVVEALVGLGFAAKQAEEATDTVLAANHDATTSSALRSALSLLGK

General information: TITO was launched using: RESULT: Template: 2ZTD.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 756 -11012 -14.57 -62.57 target 2D structure prediction score : 0.66 Monomeric hydrophicity matching model chain A : 0.75 3D Compatibility (PKB) : -14.57 2D Compatibility (Sec. Struct. Predict.) : 0.66 1D Compatibility (Hydrophobicity) : 0.75 QMean score : 0.618

(partial model without unconserved sides chains): PDB file : Tito_2ZTD.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2ZTD-query.scw PDB file : Tito_Scwrl_2ZTD.pdb: