Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MERKTVLYIAVSLDGMIAKEDGSIDWLDEFEGE--GDNGYSDFYQTVDTVILGRSTYEHVKVLTPVFPYQDKTCYVFTGSPDSY-QDEHVTFINEGARAFTARLKQ-EKGSNIWIAGGAELVNDFMKEDAIDEFIITVIPVVLGSGIPLFHELTNETKLRLKGTKQFGQAVQLHYVRA 2XW7 Chain:A ((2-174)) HMVKTVYYTASSLDGYIVDENQSLDWLTSRDITPDGPFGYEQFIETIGVLVMGASTYEWVVE-HGDWSY-DQPAWVLTHRPEIAAESHPMQVFSGDVAELHPELVAAAGGKDVWVVGGGDVAAQFVAADLIDEIIVSYAPCTLGVGSRVLPM---RSEWVLDDCARNGDFVCARWKRP

General information: TITO was launched using: RESULT: Template: 2XW7.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 819 -30267 -36.96 -179.09 target 2D structure prediction score : 0.52 Monomeric hydrophicity matching model chain A : 0.76 3D Compatibility (PKB) : -36.96 2D Compatibility (Sec. Struct. Predict.) : 0.52 1D Compatibility (Hydrophobicity) : 0.76 QMean score : 0.608

(partial model without unconserved sides chains): PDB file : Tito_2XW7.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2XW7-query.scw PDB file : Tito_Scwrl_2XW7.pdb: