Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEKDGLCRADQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIREVAVLRHLETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTETIKDMMFQLLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQMALTSVVVTLWYRAPEVLLQSS-YATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLPGEEDWPRDVALP--RQAFHSKSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYSALSHPYFQDLERCKENLDSHLPPSQNTSELNTA 5D1J Chain:A ((2-291)) ----------ENFQKVEKIGE--YGVVYKARN-KLTGEVVALKKIR--------------EISLLKELN---HPNIVKLLDVIHT-----ENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADF----------------VTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL--------------

General information: TITO was launched using: RESULT: Template: 5D1J.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -159364 for 1932 contacts (-82.5/contact) + 2D Compatibility (PS) -26684 + (NN) -12520 + (LL) 3784 1D Compatibility (HY) -31600 + (ID) 6600 Total energy: -232984.0 ( -120.59 by residue) QMean score : 0.726

(partial model without unconserved sides chains): PDB file : Tito_5D1J.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5D1J-query.scw PDB file : Tito_Scwrl_5D1J.pdb: